Search on: CORE BINDING FACTOR ALPHA SUBUNITS 
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Descriptor English:   Core Binding Factor alpha Subunits 
Descriptor Spanish:   Subunidades alfa del Factor de Unión al Sitio Principal 
Descriptor Portuguese:   Subunidades alfa de Fatores de Ligação ao Core 
Synonyms English:   Acute Myeloid Leukemia Proteins
PEBP2A Transcription Factors
Polyomavirus Enhancer A Binding Protein 2
Polyomavirus Enhancer Binding Protein 2, Alpha Subunit
Runt Domain Factor
Runx Proteins
Transcription Factors, PEBP2A
Core Binding Factor alpha Proteins  
Tree Number:   D12.776.930.155.200
Definition English:   A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression. 
History Note English:   2006(1987) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51175 
Unique Identifier:   D050657 

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